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Index > Protein center > Crlf2(Gene name) > Mouse
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  • Crlf2 (Gene name),
  • Cytokine receptor-like factor 2 (Protein name ),  CRLF2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Crlf2(Crlm2;Tpte2;Tslpr);
    Protein name:
    Cytokine receptor-like factor 2;
    Alternative:
    Thymic stromal lymphopoietin protein receptor(TSLP receptor);Cytokine receptor-like molecule 2(CRLM-2);Type I cytokine receptor delta 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer of CRLF2 and IL7R.
    Function:
    Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system.
    Subcellular Location:
    Isoform 2 Secreted
    Protein Attributes:
    Sequence length:
    359
    Sequence:
    50:
    MAWALAVILL | PRLLAAAAAA | AAVTSRGDVT | VVCHDLETVE | VTWGSGPDHH | 
    100:
    GANLSLEFRY | GTGALQPCPR | YFLSGAGVTS | GCILPAARAG | LLELALRDGG | 
    150:
    GAMVFKARQR | ASAWLKPRPP | WNVTLLWTPD | GDVTVSWPAH | SYLGLDYEVQ | 
    200:
    HRESNDDEDA | WQTTSGPCCD | LTVGGLDPAR | CYDFRVRASP | RAAHYGLEAQ | 
    250:
    PSEWTAVTRL | SGAASAASCT | ASPAPSPALA | PPLLPLGCGL | AALLTLSLLL | 
    300:
    AALRLRRVKD | ALLPCVPDPS | GSFPGLFEKH | HGNFQAWIAD | AQATAPPART | 
    350:
    EEEDDLIHPK | AKRVEPEDGT | SLCTVPRPPS | FEPRGPGGGA | MVSVGGATFM | 
    359:
    VGDSGYMTL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cytokine receptor-like factor 2
    Cat.:
    E11720r
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Cytokine receptor-like factor 2
    Cat.:
    E11720m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Cytokine receptor-like factor 2
    Cat.:
    E11720h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cytokine receptor-like factor 2
    Cat.:
    U11720r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cytokine receptor-like factor 2
    Cat.:
    U11720h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cytokine receptor-like factor 2
    Cat.:
    U11720m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Cytokine receptor-like factor 2
    Cat.:
    P11720Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cytokine receptor-like factor 2
    Cat.:
    P11720Rb-h
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    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cytokine receptor-like factor 2
    Cat.:
    P11720Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Cytokine receptor-like factor 2
    Monoclonal Antibody for Mouse Cytokine receptor-like factor 2
    Monoclonal Antibody for Mouse Cytokine receptor-like factor 2
    Protein for Mouse Cytokine receptor-like factor 2
    Protein for Mouse Cytokine receptor-like factor 2
    Protein for Mouse Cytokine receptor-like factor 2

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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular cloning and characterization of CRLM-2, a novel type I cytokine receptor preferentially expressed in hematopoietic cells."
      Hiroyama T. , Iwama A. , Morita Y. , Nakamura Y. , Shibuya A. , Nakauchi H.
      Biochem. Biophys. Res. Commun.272:224-229(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: Embryo.
    2. 2.
      "Molecular cloning of a novel type I cytokine receptor similar to the common gamma chain."
      Fujio K. , Nosaka T. , Kojima T. , Kawashima T. , Yahata T. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Yamamoto K. , Nishimura T. , Kitamura T.
      Blood95:2204-2210(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);ALTERNATIVE SPLICING
      tissue: Lymphocyte.
    3. 3.
      "Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor. Formation Of a functional heteromeric complex requires interleukin 7 receptor."
      Park L.S. , Martin U. , Garka K. , Gliniak B. , Di Santo J.P. , Muller W. , Largaespada D.A. , Copeland N.G. , Jenkins N.A. , Farr A.G. , Ziegler S.F. , Morrissey P.J. , Paxton R. , Sims J.E.
      J. Exp. Med.192:659-670(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION AS A RECEPTOR FOR TSLP
      strain: C57BL/6.
      tissue: Lymphocyte.
    4. 4.
      "Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin."
      Pandey A. , Ozaki K. , Baumann H. , Levin S.D. , Puel A. , Farr A.G. , Ziegler S.F. , Leonard W.J. , Lodish H.F.
      Nat. Immunol.1:59-64(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
    5. 5.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      strain: C57BL/6J.
      tissue: Embryonic stem cell.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: FVB/N.
      tissue: Mammary gland.
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